Original
By certification 
Cefoperazone Sodium and Sulbactam Sodium Mixture 
Product |
Cefoperazone Sodium and Sulbactam Sodium Mixture |
|
Ratio: |
1:1 |
2:1 |
Synonyms: |
Cefoperazone Sodium Sulbactam Sodium |
|
Characteristics: |
White powder. |
|
Usage: Cefoperazone Sodium and Sulbactam Sodium Mixure. Because Sulbactam also binds with some penicillin-binding proteins, sensitive strains are also often rendered more susceptible to cefoperazone together with sulbactam than to cefoperazone alone.
Certificate of Analysis: Cefoperazone Sodium and Sulbactam Sodium (1:1)
Product |
Cefoperazone Sodium and Sulbactam Sodium (1:1) |
|
Testing Item |
Standard |
Result |
Appearance |
White to slightly yellow powder or crystalline powder. |
Almost white powder |
Identification A |
The HPLC RT should correspond to that of reference standard. |
Complies |
Identification B |
Yields the flame reaction of sodium. |
Complies |
pH |
3.5 ~ 6.5 |
5.3 |
Clarity of solution |
≤ 1# |
< 0.25# |
Color of solution |
≤ 4# (Y or YG) |
< 2Y# |
Water |
≤ 4.0% |
2.1% |
Related Substances |
Impurity A≤ 1.5% Any single impurity ≤1.5% Other total impurities≤ 5.0% |
0.1% 0.4% 1.4% |
Visible Particles |
Conforms |
Conforms |
Paticulate matter |
≥10 μm ≤ 6000 particle/4.0g ≥25 μm ≤ 600 particle/4.0g |
165 particle/4.0g 0 particle/4.0g |
Bacterial Endotoxins |
≤ 0.050EU/mg |
0.005EU/mg |
Sterility |
Should meet the requirement |
Complies |
Assay |
Cefoperazone ≥435ug/mg Sulbactam ≥445ug/mg |
462.5ug/mg 462.5ug/mg |
Ratio of Cefoperazone Sodium and Sulbactam Sodium |
0.97~1.05 |
1.00 |
